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Deficiencies and overuse of these vitamins can lead to clinical manifestations.The most clinically important fat-soluble vitamins are the vitamins A, D, E, and K.They are divided into water-soluble and fat-soluble vitamins.
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These substances cannot be synthesized by the body they must be ingested in the diet. Vitamins are important organic substances that are required for normal metabolic functions. Because these vitamins are fat-soluble and stored in the body, overuse of supplemental vitamins may lead to toxicity and adverse effects, especially with vitamins A and D. Diagnosis of deficiencies is by clinical presentation and lab testing, and management of vitamin deficiency is with supplementation. Each vitamin has its own function, and deficiencies can lead to significant clinical manifestations.
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The 4 important fat-soluble vitamins are A, D, E, and K. These vitamins can be released from storage and used when necessary. Its main functions are detoxification, metabolism, nutrient storage (e.g., iron and vitamins), synthesis of coagulation factors, formation of bile, filtration, and storage of blood. The liver is found in the superior right quadrant of the abdomen and weighs approximately 1.5 kilograms. Adipose Tissue (fat) and the liver Liver The liver is the largest gland in the human body. There are three types of adipose tissue, white adipose tissue, brown adipose tissue, and beige or "brite" adipose tissue, which is a transitional form.